OPTIMAL: An OPTimzed Imaging Mass Cytometry AnaLysis approach for Segmentation and Data Exploration

We are delighted to have Dr. Andrew Filby, Director of the Newcastle Flow Cytometry Core Facility, part of the Newcastle University Single Cell Unit and Lead of the Innovation, Methodology and Application (IMA) Research Theme, as our next Scientist in the Spotlight.

In this talk, Dr Filby will present OPTIMAL, a framework for optimizing and validating existing tools for single-cell segmentation of multiplexed tissue images, data QC and normalization as well as clustering and spatial neighborhood analysis. Dr Filby will present this approach both in the context of well-characterized human tonsil tissue as a benchmark but also as part of the UK Coronavirus Immunology Consortium (UK-CIC) project using Imaging Mass Cytometry™ to understand disease progression in post-mortem tissues.

Join this webinar to learn the value of high-plex imaging and how to obtain accurate, biologically validated single-cell phenotypic data in these experiments.

01:08:00