Mechanical properties of biological tissues and cells are important parameters that influence their healthy functioning and play an important role in diseases. In cell cultures, mechanical microenvironment, such as substrate stiffness or external forces, have been shown to influence cell morphology, biochemical signaling and differentiation. In tissue engineering, the mechanics of tissue constructs need to match the native ones.
Mechanics have the potential to be label-free biomarker for diagnostic, drug development, biofabrication and quality control applications. Thereby, Optics11 Life developed the first high-throughput mechanical screening platform. The Pavone combines state-of-the-art fiber-optics force-sensing technology with integrated imaging and precision mechatronics to provide one solution for any mechanical analysis challenge.
During the webinar, we will discuss why we need high-throughput mechanical testing when studying biomaterials, overview Pavone functionality, and show results of mechanical phenotyping of cells, and quality control of hydrogel production.