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Message preview	Hi there, You are invited to a Zoom webinar. When: Jun 22, 2022 06:00 PM Eastern Time (US and Canada) Topic: Gut Development and Neurodegenerative Disorders - June 22, 2022 ‐ 6 pm ET/5 pm CT/3 pm PT Register in advance for this webinar: https://us06web.zoom.us/webinar/register/WN_8Jyh9jf6SLu4KtieumHwzw After registering, you will receive a confirmation email containing information about joining the webinar. ---------- Webinar Speakers Robert Heuckeroth, MD, PhD (Research Director and Norman and Irma Braman Endowed Chair of CHOP's Lustgarten Center for GI Motility @Children's Hospital of Philadelphia) Robert Heuckeroth, MD, PhD, is a pediatric gastroenterologist in the Division of Gastroenterology, Hepatology and Nutrition at Children's Hospital of Philadelphia. He is also Research Director and Norman and Irma Braman Endowed Chair of CHOP's Lustgarten Center for GI Motility. Areas of Expertise: Hirschprung's Disease, Chronic intestinal pseudo-obstruction syndrome, Intestinal motility disorders, Malnutrition, Genetics of gastrointestinal disease. E. Michelle Southard-Smith, PhD (Professor of Medicine and Cell and Developmental Biology @Vanderbilt University) Dr. Southard-Smith is a tenured Professor in the Department of Medicine at Vanderbilt University Medical Center with a joint appointment in the Department of Cell and Developmental Biology at Vanderbilt University. She earned her Bachelors degree from the University of Oklahoma, where she graduated with special distinction (Summa Cum Laude). Our group is focused on understanding how discrete disease genes work individually and in combination with other genes in the genetic background to produce deficits of the peripheral nervous system. Our efforts are concentrated on two aspects of visceral organ innervation: the enteric nervous system (ENS), a network of interconnected ganglia in the wall of the intestine that controls gut motility; and pelvic nerves that control bladder emptying in the lower urinary tract (LUT). Art Beyder, MD, PhD (Associate Professor of Medicine and Physiology @Mayo Clinic, Rochester) Dr. Beyder runs an NIH-funded research program, which aims to determine the mechanisms of “gut feelings” and how these mechanisms are disrupted in gastrointestinal motility disorders. His specific expertise is in the mechanical and electrical aspects of the digestive system function. His work has focused on the cellular and molecular aspects of ion channel physiology and biophysics in the gut and how forces are sensed and transduced by these ion channels. The NIH funds Dr. Beyder’s group, and recently their work was recognized by the NIH Director’s New Innovator Award, recognizing the creativity of their work. He has published in high-impact journals, like PNAS, JCI, Circulation, Gastroenterology, and Journal of Physiology. Dr. Beyder also holds several US patents. Kristen M. Smith-Edwards, PhD (Senior Postdoctoral Associate @University of Pittsburgh) Dr. Kristen Smith-Edwards is completing her postdoctoral training at the University of Pittsburgh and begins her faculty appointment as Assistant Professor at the Mayo Clinic in August. Her research is focused on the neural circuits of the gut-brain axis that control organ function in health and disease. She has optimized in vivo and ex vivo optogenetic and calcium imaging approaches to record cell-to-cell interactions between peripheral neuron circuits (enteric, autonomic and sensory) and target cells in the bowel that regulate motility, inflammation, and visceral pain. She is specifically interested in neuro-immune-microbiome interactions during postnatal development of the enteric nervous system that lead to chronic gastrointestinal issues and disease.

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