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Familial Hypercholesterolaemia as an evidence-based model of innovation in CVD
Cardiovascular diseases (CVD) account for one third of global deaths and are the main cause of mortality worldwide. In low- and middle-income countries, 80% of the deaths are associated with CVD. The World Health Organization aims to reduce premature mortality due to non-communicable diseases by at least 30% by 2030.

The diseases that cause the greatest global burden, such as the CVD, are multifactorial. It is estimated that up to 75% of premature CVD is preventable. Traditional CVD management is largely aimed at changing lifestyle-related factors. However, advances in genomic medicine allow for a more comprehensive approach: accurate diagnosis, improvement in risk stratification and targeted treatment. The value of precision medicine is defined by all the data that can be generated about an individual. Advances go beyond isolated clinical data, imaging or classical laboratory tests, toward the integration of more complex data sets (genomics, metabolomics, proteomics and so on), sometimes called “panomic profiling”. The applications of genomics and emerging sciences have the potential to revolutionize the prevention, diagnosis and treatment of cardiovascular diseases, following the model that already revolutionized oncology. Personalized medicine refers to the implementation of such data in a patient-specific plan using biomarkers.
Classic approaches in contemporary cardiology cannot yet explain why, for example, myocardial infarction also occurs in young people or why a person with an apparently "healthy" lifestyle is at very high cardiovascular risk.

The FH Awareness Day webinar aims to answer the following questions:

1. How has innovation changed life expectancy and quality of life for FH patients and their families?
2. How can we imagine the future of FH and what is the role of patients and citizens?
3. What role will data and technology play in FH management?
4. Why should patients/citizens be interested in innovation and personalized medicine in cardiology?

Sep 24, 2021 05:30 PM in Zurich

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Dr. Marius Geanta
FH Europe Trustee and Co-Chair @Scientific and Public Health Advisory Committee and Co-Founder & President of InnoMed Center for Innovation in Medicine
Prof. Mafalda Bourbon
Head of the Cardiovascular Research Group @The National Institute of Health Portugal
Prof. Dr. Hans Lehrach
Director and Scientific Member @Max Planck Institute for Molecular Genetics
Prof. Kausik Ray
President @European Atherosclerosis Society, EAS FH Studies Collaboration Lead