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Advanced in vitro methods in generic drug product development
The use of Pion equipment within Zentiva development will be presented. Zentiva is a generic company and thus applications for the development of generics will be discussed.

Topics covered:

• Physicochemical characterization of APIs using T3
• Screening of API solid forms using InForm
• Precipitation experiments on InForm – screening of precipitation inhibitors and description of factors influencing repeatability of the experiments
• MacroFlux – indirect identification of API-excipient interactions and risk mitigation for bioequivalence studies
• Rainbow fiberoptic system – use for precipitating systems, comparison with standard offline analysis (UV/HPLC)

Nov 10, 2022 11:00 AM in Eastern Time (US and Canada)

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